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景岳生技研發腳步突破到不同產品未來可以殺死胰臟癌 肺腺癌 肝癌 乳癌癌細胞

Posted On By CoCo可

【記者 彭 可/台北報導】

景岳生技研發腳步突破到不同產品未來可以殺死胰臟癌、肺腺癌、肝癌、乳癌癌細胞。

高哲翰教授表示,曾連任5屆立法委員的陳根德,如今淡出政壇,專心經營景岳生技事業、擔任大園區仁壽宮董事長,效法仁壽宮感天大帝的忠孝精神,服務地方公共事務,反而讓他生活海闊天空,冷眼旁觀時事更為精闢,他說,商場經歷厚植從政的基礎,走下政治舞台,更有空間做公益、為弱勢族群盡棉薄之力。尤其景岳生技股份有限公司董事長陳根德研究團隊表示:

▲國際醫學期刊SCi登載的論文。

1. The synergistic tumor growth-inhibitory effect of probiotic基因轉殖胰臟癌動物模式證實,乳酸桿菌合併化療藥物(Gemcitabine)使用,可發揮抑制癌細胞生長的協同作用胰臟癌屬於世界上最致命且對化療藥物具有抗藥性的癌症之一。目前對於腸道微生物態在宿主抗癌治療的效果上扮演重要的調節角色這一理論,隨著累積的證據也逐漸獲得支持。 景岳生技股份有限公司研究團隊表示,本篇研究重點在探討胰臟癌化療期間給予益生菌,其可發揮的輔助作用。作者利用LSL-Kras G12D/− ‑Pdx‑1‑Cre基因轉殖鼠的胰管腺癌 (Pancreaticductaladenocarcinoma; PDAC)註1動物模型,給予4周複合菌(Lactobacillus paracasei GMNL‑133和Lactobacillus reuteri 。GMNL‑89),來評估利用複合菌株作為化療輔助療法時,對於控制癌症發展的影響。

 

2. Lactobacillus Attenuate the Progression of Pancreatic Cancer運用K-rasG12D 基因轉殖小鼠的胰臟癌動物模式證實,乳酸桿菌可減弱牙齦卟啉菌(P. Gingivalis) 促進的癌症發展 (抑制胰臟癌惡化)本篇主要在釐清P. gingivalis促發胰臟癌的原因和益生菌潛在的免疫調節能力。作者利用6周齡大的KC(基因轉殖胰臟癌)小鼠,塗抹P. gingivalis在牙齦上,4周後誘發的胰臟上皮內腫瘤 (pancreatic intraepithelial neoplasia, PanIN) 。

其病變程度與未給予P. gingivalis刺激的24周大KC小鼠相似。P. gingivalis合併給予益生菌的小鼠胰臟重量明顯低於單獨給予P. gingivalis (P = 0.0028)小鼠,從組織病理學上也可觀察到胰臟細胞的Snail-1、 ZEB-1、collagen fibers、Galectin-3和PD-L1表現量明顯降低。此外,給予P. gingivalis刺激下的KC小鼠益生菌,可減少Smad3 和磷酸化Smad3在組織上的表現量。作者證明了讓口腔暴露於P. gingivalis的刺激下會促使胰臟上皮內腫瘤惡化,而益生菌則有益於減少癌細胞增生和生存力、抑制胰臟上皮內腫瘤 (PanIN)發展和癌細胞轉移(上皮細胞間質轉化EMT),其機制可能與TGF-β訊號傳遞有關。這是國際醫學期刊SCi登載的論文。景岳生技股份有限公司研究團隊更表示,景岳研發腳步已經突破到不同的產品可以殺死胰臟癌、肺腺癌、肝癌、乳癌癌細胞。

景岳生技研究團隊,不僅立足台灣 、邁向世界, 可喜可賀。這個不容易 ,十幾個教授 集思廣益 、集體創作、 腦力激盪 、眾志成城。景岳生技董事長陳根德表示,過去在政治舞台上,盡力服務人民、為人民權益謀福利,如今走下政治舞台,心情愉快,人生規畫重心轉到公益、幫助弱勢及公共服務。他自詡經商、從政口碑可受公評,強調「信譽和原則」是他做人、處事,一路走來堅持的信念。

▲「警界孔子」,前警大教授 、中央警察大學教授兼主任、前警專 台灣警察專科學校 教授、台視《台灣變色龍》評論人、八大第一台《暗光鳥新聞》主持人 ,前環球科技大學文創學院院長、 華夏科技大學副校長兼商管學院院長、崇右影藝科技大學副校長兼表演藝術學院院長、 影視設計學院院長 ,現任:双子衛視電視台首席顧問知名主持人高哲翰講座教授。

CoCo可
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有情有義,人與人之間、最大的吸引力,不是容顏、不是財富,也不是才華、是傳遞給對方的信賴和踏實、真誠和善良。 人生並不全是競爭和利益,更多的是共贏 懂得感恩、便會幸運!

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